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Comfort Food Bliss: Easy Chicken Pot Pie Casserole Recipe

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If you’re looking for a hearty, comforting dish that’s as easy to make as it is delicious, this Chicken Pot Pie Casserole is for you! This family-friendly dinner takes all the cozy flavors of a classic chicken pot pie and simplifies it into a quick casserole topped with golden, buttery biscuits. Packed with tender chicken, savory vegetables, and a rich, creamy sauce, it’s sure to be a hit with everyone at the table.

Chicken Pot Pie Casserole

Chicken Pot Pie Casserole

What makes this recipe a winner? It’s quick to prepare, uses simple ingredients, and delivers big on flavor. Whether it’s a busy weeknight or a cozy weekend dinner, this casserole is the perfect go-to meal when you need something satisfying without spending hours in the kitchen. Plus, the flaky biscuits make it irresistible!

Not only is this dish a time-saver, but it’s also highly customizable. Use whatever veggies you have on hand, swap out the cheese for a different variety, or add extra seasonings to suit your taste. This Chicken Pot Pie Casserole is all about bringing comfort food to your table—your way!

chicken pot pie casserole

What You Will Love About This Recipe

Quick and Easy: With simple ingredients like canned biscuits and cream of chicken soup, you can whip this up with minimal prep time.


Customizable: Use rotisserie chicken, your favorite veggies, or even a different type of cheese to make it your own.


Crowd-Pleaser: Perfect for family dinners, potlucks, or when you want to wow your guests with a cozy meal.

Chicken Pot Pie Casserole

Ingredients

  • 2 chicken breasts, cooked & cut into ½ inch cubes (about 2-3 cups)
  • 1 (10.5-ounce) can cream of chicken soup
  • ½ cup milk
  • ½ cup sour cream
  • 1 teaspoon onion powder or 1 tablespoon minced onion
  • ½ teaspoon seasoned salt
  • ⅛ teaspoon pepper
  • 1 ½ cups shredded cheddar cheese, divided
  • 2 cups cooked mixed veggies
  • 1 can refrigerated biscuits (I used Grands)
  • 1 tablespoon butter, melted

How to Make 

  • Preheat the oven to 375°F. Grease a 9×13 glass or ceramic baking dish.
  • In a large bowl, using only 1 cup of the shredded cheese, mix together all ingredients except for the biscuits and melted butter.
  • Pour chicken mixture into the prepared baking dish. Bake uncovered for 15 minutes. Remove from oven and stir. Sprinkle the remaining ½ cup of cheese on top of the mixture.
  • Separate each biscuit in half, dividing the top and bottom so that they aren’t as thick. Place 12 biscuits on top of the chicken and cheese mixture (do not overlap biscuits).
  • Bake for another 15-20 minutes or until biscuits are browned and cooked through.
  • Brush tops of biscuits with melted butter and serve!
Chicken Pot Pie Casserole

Tips & Tricks

  • Prep Ahead: Cook your chicken and veggies ahead of time to save time on busy weeknights.
  • Cheese Swap: Not a cheddar fan? Try mozzarella or a blend of Monterey Jack and Parmesan for a different flavor profile.
  • Crispy Biscuit Hack: For extra-crispy biscuit tops, bake the biscuits separately on a sheet pan for a few minutes before adding them to the casserole.
  • Add a Little Crunch: Sprinkle a handful of crushed Ritz crackers or fried onions on top of the cheese before baking for a crunchy topping.
  • Don’t Overlap the Biscuits: To ensure they bake evenly, place the biscuits side-by-side without overlapping.
Chicken Pot Pie Casserole

FAQs

Absolutely! Using canned or rotisserie chicken is a great way to save time. Just shred or cube it, and you’re good to go.

Yes! You can prepare the chicken mixture and store it in the fridge for up to 24 hours. When you’re ready to bake, just add the biscuits and cook as directed.

Store any leftovers in an airtight container in the fridge for up to 3 days. Reheat in the oven or microwave until warmed through.

Chicken Pot Pie Casserole
chicken pot pie casserole long pin
Chicken Pot Pie Casserole

Chicken Pot Pie Casserole

Prep Time: 15 minutes
Cook Time: 30 minutes
Total Time: 45 minutes

Serve up this chicken pot pie casserole for your weeknight dinner this week. Creamy chicken pot pie filling topped with diced up biscuits and baked until they are golden brown. This pot pie bake is so simple to make. 

Ingredients

  • 2 chicken breasts, cooked & cut into ½ inch cubes (about 2-3 cups)
  • 1 (10.5-ounce) can cream of chicken soup
  • ½ cup milk
  • ½ cup sour cream
  • 1 teaspoon onion powder or 1 tablespoon minced onion
  • ½ teaspoon seasoned salt
  • ⅛ teaspoon pepper
  • 1 ½ cups shredded cheddar cheese, divided
  • 2 cups cooked mixed veggies
  • 1 can refrigerated biscuits (I used Grands)
  • 1 tablespoon butter, melted

Instructions

  1. Preheat the oven to 375°F. Grease a 9x13 glass or ceramic baking dish.
  2. In a large bowl, using only 1 cup of the shredded cheese, mix together all ingredients except for the biscuits and melted butter.
  3. Pour chicken mixture into the prepared baking dish. Bake uncovered for 15 minutes. Remove from oven and stir. Sprinkle the remaining ½ cup of cheese on top of the mixture.
  4. Separate each biscuit in half, dividing the top and bottom so that they aren’t as thick. Place 12 biscuits on top of the chicken and cheese mixture (do not overlap biscuits).
  5. Bake for another 15-20 minutes or until biscuits are browned and cooked through.
  6. Brush tops of biscuits with melted butter and serve!

Nutrition Information:

Yield:

8

Serving Size:

1

Amount Per Serving: Calories: 238Total Fat: 15gSaturated Fat: 7gTrans Fat: 0gUnsaturated Fat: 6gCholesterol: 61mgSodium: 444mgCarbohydrates: 9gFiber: 1gSugar: 3gProtein: 17g

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